We are seeking a highly motivated Associate Director to support Pharmacokinetics (PK) and Preclinical Pharmacokinetics/Pharmacodynamics (PPK/PD) requirements for Discovery and IND-stage project teams. You will provide PK and PK/PD input and direction to early preclinical/nonclinical in vivo studies in collaboration with TFA scientific staff. You will prepare and present the PK/PD analyses to internal project teams and senior management, as well as writing summary reports and documents to support regulatory filings.

As an Associate Director, a typical day might include:

• Serving on Discovery-stage project teams as a subject matter authority for Preclinical Pharmacokinetics/Pharmacodynamics, providing input to the design of preclinical PK/pharmacology studies

• Collaborating optimally with various groups within Regeneron to develop and carry out a PK strategy for each project

• Effectively communicating project team queries, requests, and expectations (i.e. timing and results) from the project teams to management

• Conducting and reporting PPK/PD analyses using data derived from preclinical (nonclinical) studies

• Working in close association with the Toxicology, Pathology, Clinical Pharmacology (CP) and Quantitative Pharmacology (modeling & simulation) functions, within the Drug Safety and Pharmacometrics (DSP) Department, to deliver the required data and study reports/regulatory documents to support project progression.

• Maintaining an up-to-date knowledge of the relevant scientific literature as well as regulatory guidance and best practices

This role might be for you if you:

• Enjoy working in a fast-paced, highly collaborative culture

• Have a passion for science and want to help bring new drugs to people in need

• Are excited work across multiple therapeutic areas and new modalities

• Have excellent communication (written/verbal), presentation, influencing and leadership skills

In order to be considered for this role, you must have at least a Ph.D. in Pharmacology, Pharmacokinetics, Biology/Molecular Biology or Biochemistry, with 8-10+ years or a BS/MS and 15+ years of relevant experience in a biotech or pharmaceutical industry setting. We need someone with an in-depth theoretical and applied understanding of PK and PD, in order to describe and understand the pharmacology/biology of therapeutic proteins. Experience with other modalities including siRNA and CRISPR based therapeutics, and cell therapies is highly advantageous. Must have experience with planning, coordinating, and leading all aspects of PK and/or PK/PD studies and analyzing PK/PD data. Experience with protein/monoclonal antibody therapeutics and new modalities in one or more of the following therapeutic areas: oncology, inflammation/immunology, metabolism, infectious disease or ophthalmology is required. Must have experience with relevant PK/PD software applications (e.g., WinNonLin) as well as experience in drafting PK reports and relevant IND sections.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.

Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.

Salary Range (annually)

$173,500.00 - $283,100.00