Job Information
Rutgers The State University Post Doctoral Associate in New Brunswick, New Jersey
Position Details
Recruitment/Posting Title | Post Doctoral Associate |
---|---|
Department | Engn - Biomedical Engineering |
Salary | Commensurate With Experience |
Posting Summary | This position seeks a Post Doctoral Associate to develop a microfluidics single cell 'smart' electroporation system. This system consists of a microfluidic device that automatically detects the entrance of an individual cell into an electroporation zone, and subsequently applies a user-defined electroporation pulse to the cell in transit. Cell membrane impedance is continuously monitored, and both optical and electrical measurements are conducted before and immediately after pulse application. Cells are assayed for viability, delivery of small molecules, nucleic acids, etc. The system will also implement a feedback control algorithm with determined electrical thresholds to module the pulse parameters required by a single cell within the system. A successful candidate will characterize the performance of the system for various cell types (especially hard to transfect primary human dermal fibroblasts (HDFs), and lymphoblastoid cells (LCLs)) and delivery vectors for iPSC generation, CRISPR/Cas9 gene editing, CAR T Cell generation and other immune-editing vectors, and compare the microfluidics system to current standard EP systems. You will also begin to scale up the throughput of the microfluidic system to increase cell processing rates. These studies will therefore provide the first stepping stones towards future product development for a 'smart' electroporation system. This is an ongoing collaborative project with multiple faculty at Rutgers and an industrial sponsor. The candidate must engage with other personnel on the project and provide guidance and mentoring to undergraduate and graduate students. It is expected that the work will yield several high impact academic publications and presentations at national/international conferences. |
Position Status | |
Posting Number | 19FA2219 |
Posting Open Date | 10/09/2019 |
Posting Close Date |
Minimum Education and Experience | PhD in biomedical engineering, electrical engineering, chemical engineering, or closely related field. Be familiar with general concepts about lab safety and procedures. |
---|---|
Certifications/Licenses | |
Required Knowledge, Skills, and Abilities | PhD level is required because creative experimental design is inherently part of the development of the electroporation system. At least 5 years' experience with microfluidics, microfabrication, biosensors or similar areas, 1 year experience with cell culture, biochemical and molecular biology assays, 2 years' experience with Labview are preferred |
Equipment Utilized | Optical Lithography Mask Aligner, Physical Vapor Deposition Sputtering System, |
Physical Demands and Work Environment | Expect to spend several hours per day in the lab and microfabrication facility, which involves standing for long periods of time. |
Overview | |
Statement |
Special Instructions to Applicants | |
---|---|
Quick Link to Posting | https://jobs.rutgers.edu/postings/102888 |
Campus | Rutgers University-New Brunswick |
Home Location Campus | Busch (RU-New Brunswick) |
City | |
State | |
Location Details |
Under Policy 100.3.1 Immunization Policy for Covered Individuals, if employment will commence during Flu Season, Rutgers University may require certain prospective employees to provide proof that they are vaccinated against Seasonal Influenza for the current Flu Season, unless the University has granted the individual a medical or religious exemption. Additional infection control and safety policies may apply. Prospective employees should speak with their hiring manager to determine which policies apply to the role or position for which they are applying. Failure to provide proof of vaccination for any required vaccines or obtain a medical or religious exemption from the University will result in rescission of a candidate's offer of employment or disciplinary action up to and including termination.
It is university policy to provide equal employment opportunity to all its employees and applicants for employment regardless of their race, creed, color, national origin, age, ancestry, nationality, marital or domestic partnership or civil union status, sex, p regnancy, gender identity or expression, disability status, liability for military service, protected veteran status, affectional or sexual orientation, atypical cellular or blood trait, genetic information (including the refusal to submit to genetic testing), or any other category protected by law. As an institution, we value diversity of background and opinion, and prohibit discrimination or harassment on the basis of any legally protected class in the areas of hiring, recruitment, promotion, transfer, demotion, training, compensation, pay, fringe benefits, layoff, termination or any other terms and conditions of employment. For additional information please see the Non-Discrimination Statement at the following web address: http://uhr.rutgers.edu/non-discrimination-statement