Highly motivated individuals with a PhD or MD/PhD in relevant area are encouraged to apply. This training position, under the direct supervision of a Cleveland Clinic Principal Investigator will provide practical training and experience in a research setting. This position is appointed through the Lerner Research Institute. The successful applicant will be able to demonstrate a commitment to research, a collaborative work ethic and strong communication skills, both written and verbal. This program is expected to be completed within 5 years.

Principal Investigator: Srinivasan Dasarathy, MD

Lerner Research Institute Department: Inflammation & Immunity

Lab Research Topics:

• Cell signaling

• RNA translation

• Biochemistry

• Gene editing

• Imaging

• For more information about the lab's research, please visit: https://www.lerner.ccf.org/immuno/dasarathy/ or contact Dr. Dasarathy at dasaras@ccf.org .

Job Responsibilities:

• Independent project design with the goal of data generation, analysis, interpretation and manuscript preparation

• Culture of multiple cell lines, primary cell cultures

• Basic molecular methods (real time PCR, immunoblots)

• Confocal microscopy, fluorescent imaging

• mRNA translational regulation

Education:

• PhD or MD/PhD required

• MD with relevant laboratory experience may substitute for PhD

Languages:

• English Proficiency proof required for candidates arriving on J-1, J-2, or F1 + OPT visa status

Work Experience:

• Previous experience in a research or academic setting. Graduate student experience meets this requirement.

• Scientific writing experience

Additional Preferred Qualities:

• Crispr/Cas9

• Viral delivery systems

• Handling mouse strains (not essential)

• Protein expression, protein-protein interaction studies

• Fraction separation, organelle isolation

• Ability to analyze and perform mass spectrometry data for metabolites preferred but not essential

Physical Requirements:

• Ability to perform work in a stationary position for extended periods

• Ability to operate a computer and other office equipment

• Ability to communicate and exchange accurate information

• Ability to distinguish color

• Manual dexterity to handle specimens and repair equipment

• Ability to lift and transport equipment or specimens weighing up to 20 pounds

• May be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc.

Personal Protective Equipment:

• PPE per institutional requirements; may vary by laboratory

Preferred Application Materials:

• Cover letter

• CV

• Contact information for three references

• All application materials should be submitted directly via email to Dr. Dasarathy at dasaras@ccf.org .

Keywords: Postdoc, Research, LRI, Crispr/Cas9, Skeletal muscle, Tissue specific deletion, Inducible vector systems, Reporter analyses, FRET/BRET, Post-translational modifications, Generate tagged constructs, Subcellular organelle studies

Pay Range

Minimum hourly: $0.01

Maximum hourly: $333,340.26

The pay range displayed on this job posting reflects the anticipated range for new hires. While the pay range is displayed as an hourly rate, Cleveland Clinic recruiters will clarify whether the compensation is hourly or salary. A successful candidate's actual compensation will be determined after taking factors into consideration such as the candidate's work history, experience, skill set, and education. This is not inclusive of the value of Cleveland Clinic's benefits package, which includes among other benefits, healthcare/dental/vision and retirement.

Cleveland Clinic Health System is pleased to be an equal employment employer: Women / Minorities / Veterans / Individuals with Disabilities